Lolo

The active ingredients in Lolo are ethinyl estradiol (estrogen) and norethindrone acetate (progestin). This combination pill belongs to a class of medications called oral contraceptives. It prevents pregnancy by stopping the release of an egg from the ovaries during your menstrual cycle, known as ovulation. Additionally, it works by thickening the mucus in the cervix to block sperm from reaching the uterus.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Lolo. However, the following is a synopsis of the general guidelines for the use of Lolo:

• Take this medication orally with or without food exactly as directed by your healthcare provider.
• Take 1 blue tablet/blue pill daily for 24 days, then 1 white tablet/white pill daily for 2 days, then 1 lilac-coloured tablet daily for 2 days. Take the tablets orally at the same time daily.
• Missed doses can cause spotting or light bleeding, even when you take these missed pills later. Because this medication has a very low dose of estrogen, some women may have more breakthrough bleeding compared to other birth control pills containing higher estrogen doses.

Some mild and common side effects of Lolo seen in clinical trials as compared to placebo include:

• Headache.
• Vaginal yeast infection.
• Bloating.
• Abdominal pain.
• Breast tenderness.
• Bacterial vaginosis.
• Acne.
• Weight change (weight gain).
• Bleeding irregularities.
• Nausea.
• Vomiting.

Some individuals may experience serious side effects while using Lolo. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe allergic reactions - hives, itching, swelling, skin rash, trouble breathing.
• Heart attack.
• Deep vein thrombosis (blood clot in the leg).
• Increased blood pressure (hypertension) - chest pain, nosebleed, dizziness.
• Severe headache.
• Cancer - breast cancer, cervical cancer.
• Liver problems - fever, jaundice (yellowing of the skin), stomach pain.
• Gallbladder problems.
• Changes in menstrual bleeding - irregular bleeding/spotting.
• Depression.

These are not all of the possible side effects of Lolo. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Lolo, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

• Nodules or fibroids in the breast.
• Diabetes.
• High cholesterol or triglycerides.
• High blood pressure (hypertension).
• Headaches or migraine.
• Epilepsy.
• Depression.
• Gallbladder, heart, or kidney problems.
• History of irregular menstrual periods.
• Hereditary angioedema.
• Smoking.
• Skin darkening.
• Upcoming surgery.
• Pregnancy.
• Breastfeeding.

Boxed Warning

• Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive (COC) use, especially if you are over 35 years of age. Therefore, Lolo should not be used by women who are over 35 years of age and smoke.

• Breast cancer or other estrogen- or progestin-sensitive cancer.
• Undiagnosed abnormal vaginal bleeding.
• Over 35 years old who smokes.
• Blood clotting condition.
• Stroke.
• Coronary artery disease (CAD).
• Heart rhythm problems.
• Uncontrolled high blood pressure (hypertension).
• Diabetes with high blood pressure or organ damage.
• Migraine headaches in people over 35 years old.
• Liver disease or liver tumors.
• Take certain hepatitis C combination medications.

This medication is effective immediately if you start taking it on the first day of your period. However, if you start on any other day, make sure to use a hormone-free birth control method for the first 7 days to help prevent pregnancy.

When Lolo is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Medications for HIV, AIDS, or hepatitis C (ritonavir).
• Seizure medications (phenytoin, lamotrigine, carbamazepine).
• Topiramate.
• Barbiturates.
• Bosentan.
• Medications for fungal infections (fluconazole, itraconazole, ketoconazole).
• Rifampin.
• St. John’s wort.
• Thyroid medications.
• Tetracyclines.
• Cyclosporine.
• Theophylline.

Listed below are the available dosage forms of this medication, including:

• Lolo pill packs consist of 28 tablets in the following order:
• 24 blue tablets, each containing 1 mg norethindrone acetate and 10 mcg ethinyl estradiol.
• 2 white tablets, each containing 10 mcg ethinyl estradiol.
• 2 brown tablets, each containing 75 mg ferrous fumarate.

Store this medication at room temperature and keep it out of the reach of children. Only remove a tablet from the blister pack when you are ready to take it.

Allergan Pharmaceuticals International Limited is the pharmaceutical company that manufactures this medication.

There are no lower-cost generic options currently available for the brand-name Lolo.

Do not stop or adjust your use of this medication without first consulting your healthcare provider.

Do not take this medication while pregnant. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

This medication is known to pass through breast milk and is not recommended while breastfeeding. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.