Implanon

(Etonogestrel)

The active ingredient in Implanon is etonogestrel.

Etonogestrel is a progestin, a synthetic form of the hormone progestogen. It works mainly by stopping ovulation, meaning the ovaries do not release an egg. It also thickens cervical mucus, which makes it harder for sperm to reach the egg, and changes the lining of the uterus to reduce the chance of pregnancy.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Implanon. However, the following is a synopsis of the general guidelines for the use of Implanon:

• Implanon is inserted under the skin of the inner side of the upper arm by a healthcare provider using a special applicator.
• The insertion procedure is done using a local anesthetic to reduce discomfort.
• The implant should be placed during a specific time in your menstrual cycle to ensure you are not pregnant, often within the first 5 days of the menstrual cycle.
• In some cases, a pregnancy test may be required before insertion.
• Once inserted correctly, Implanon provides birth control for up to 3 years.
• You should be able to feel the implant under your skin after insertion.
• Removal must also be done by a trained healthcare professional, and a new implant can be inserted at the same visit if continued birth control is desired.

Some mild or common side effects of Implanon include:

• Irregular menstrual bleeding or changes in bleeding patterns.
• Headache.
• Weight gain.
• Acne.
• Breast tenderness.
• Mood swings.
• Abdominal pain.
• Nausea.
• Vaginal inflammation or discharge.
• Pain around the insertion site.

Some individuals may experience serious side effects while using Implanon. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Signs of a blood clot include chest pain, shortness of breath, or pain and swelling in the leg.
• Severe headache that is sudden or persistent.
• Yellowing of the skin or eyes may indicate liver disease.
• Severe pain in the lower abdomen could be a sign of ectopic pregnancy.
• Allergic reactions such as hives, swelling of the face or throat, or trouble breathing.
• Signs of breast cancer, such as a new breast lump.

These are not all of the possible side effects of Implanon. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Implanon, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• A history of blood clots or clotting disorders.
• Liver disease or liver tumors.
• Breast cancer or a history of breast cancer.
• Unexplained or irregular bleeding.
• High blood pressure.
• High cholesterol.
• Heart disease or a history of heart attack.
• Diabetes.
• Ovarian cysts.
• Depression or mood disorders.
• Allergies to etonogestrel or any component of the implant.

Implanon should not be used in individuals who:

• Are currently pregnant.
• Have known or suspected breast cancer.
• Have active liver disease or liver tumors.
• Have a history of serious blood clots.
• Have unexplained vaginal bleeding.
• Are allergic to etonogestrel or any component of the implant.

If Implanon is inserted during the first 5 days of your menstrual cycle, it works immediately to prevent pregnancy. If inserted at another time, a backup method of contraception should be used for the first 7 days after insertion.

When Implanon is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Certain seizure medications, which may reduce the effectiveness of Implanon.
• Rifampin, which can lower hormone levels and reduce contraceptive effectiveness.
• Some HIV medications, which may affect hormone levels.
• St. John’s wort, which may reduce contraceptive effectiveness.
• Certain birth control pills or hormonal contraceptives.
• These interactions may increase the risk of unintended pregnancy.

Implanon is available as a single subdermal implant containing 68 mg of etonogestrel.

It should be stored at room temperature, away from the reach of children or pets.

Implanon is manufactured by Organon.

Implanon is no longer available in the US. Nexplanon is the updated version that also contains etonogestrel.

Implanon must be removed by a healthcare professional. Fertility may return quickly after removal, often within days to weeks. If you do not wish to become pregnant after removal, start another effective contraceptive method immediately.

Implanon should not be used during pregnancy. If pregnancy occurs while using Implanon, the implant should be removed.

Implanon may be used while breastfeeding, but insertion is recommended no earlier than 4 weeks after childbirth. Small amounts of etonogestrel may pass into breast milk, but studies have not shown harmful effects on infants. Always discuss timing and options with your healthcare provider.