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Buy Compazine Online
(Prochlorperazine Maleate)

What is Compazine?

What is Compazine?

Compro is a prescription medication used to treat severe nausea and vomiting. It is available as a rectal suppository, which can be helpful for people who cannot keep oral medications down.

Compro is the brand name for prochlorperazine in suppository form. It may be used after surgery, during illness, or when other treatments have not worked. Because of how it works, it can also affect certain brain chemicals and may cause drowsiness or other side effects.

Order Compazine online today and save!

Purchase Compazine from Universal Drugstore today and save!

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  • All Strength's
  • 25mg

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Prochlorperazine Maleate (generic Compazine)

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Prochlorperazine Maleate 
25mg

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Important information about Compazine

The active ingredient in Compro is prochlorperazine. It works by blocking dopamine receptors in the brain, which reduces the signals that trigger nausea and vomiting. As part of the phenothiazine drug class, it also has calming effects on the central nervous system. This action helps control severe nausea and improves comfort when other treatments are not effective. Some experts describe this effect as a form of signal “simulation control,” where the medication reduces abnormal brain signaling that leads to nausea.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Compro. However, the following is a synopsis of the general guidelines for the use of Compro:

  • Compro is used as a suppository inserted into the rectum
  • Wash your hands before and after use
  • Remove the wrapper and insert the suppository as directed
  • Try to remain lying down for a few minutes after insertion
  • Use at evenly spaced times as prescribed

Some mild or common side effects of Compro include:

  • Drowsiness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Dizziness

Some individuals may experience serious side effects while using Compro. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Severe allergic reactions such as rash, swelling, or trouble breathing
  • Signs of bone marrow problems, such as sore throat, fever, or unusual fatigue
  • Muscle stiffness or unusual body movements
  • Confusion or agitation
  • Severe drop in blood pressure

These are not all of the possible side effects of Compro. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Compro, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

  • Glaucoma
  • Bone marrow disorders
  • Liver problems
  • A history of seizures
  • Pheochromocytoma
  • Difficulty urinating
  • Sensitivity to phenothiazine medications

Additional precautions include:

  • Use caution if you need to stay alert, as drowsiness is common
  • Avoid alcohol, which may increase side effects
  • This medication may affect pregnancy tests and other lab test results
  • Use caution in children due to the risk of Reye's syndrome in certain conditions

Compro should not be used in individuals who:

  • Have known hypersensitivity to prochlorperazine or other phenothiazine drugs.
  • Have severe central nervous system depression or certain bone marrow conditions.

Compro can begin to work within about 30 to 60 minutes after the suppository is inserted. Relief from severe nausea may occur relatively quickly, but the full effect may take longer depending on the individual and the cause of symptoms.

When Compro is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

  • Antihistamines such as diphenhydramine
  • Muscle relaxers or sedatives
  • Alcohol or other drugs that cause drowsiness
  • Medications that affect brain function

Compro is available as a rectal suppository in a standard strength, typically 25 mg of prochlorperazine. Your healthcare provider will determine the correct dosing schedule based on your condition and response to treatment.

Store Compro at room temperature and protect it from excessive heat. Keep suppositories in their original packaging until ready to use. Avoid storing it in areas where it may melt. Keep out of reach of children.

Compro is a brand-name medication that has been marketed by various pharmaceutical companies. Availability may vary depending on location and supplier.

Yes, Compro is available as a generic medication under the name prochlorperazine suppository. Generic versions contain the same active ingredient and are considered equally effective.

Compro is usually used for short-term treatment of severe nausea. It can generally be stopped once symptoms improve. If you have been using it regularly, speak with your healthcare provider before stopping to ensure your symptoms are properly managed.

The use of prochlorperazine during pregnancy should be carefully considered, and your healthcare provider will weigh the potential benefits and risks. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Prochlorperazine may pass into breast milk during lactation, and your healthcare provider can help determine the safest option for you and your baby. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.

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Important information about buying Compazine from UniversalDrugstore™

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Universal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

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Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Yes! We offer:

  • Up to 80% savings on medications
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  • 10% off your first order for new customers

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

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The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.