Caprelsa Drug Information
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You can easily place an order on our website in under 5 minutes. First you need to set up an account with us, create a payment method, and send us your prescriptions. Alternatively, you can order by downloading our order form or by placing an order over the phone. Delivery can take approximately 2 weeks to North America, and 4 weeks to other countries.
Caprelsa is used to treat thyroid cancer (medullary type). It works by slowing or stopping the growth of cancer cells. Vandetanib belongs to a class of drugs known as tyrosine kinase inhibitors.
Vandetanib may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting). Get medical help right away if you have any of these symptoms. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may affect the heart rhythm (see also Drug Interactions). Do not use vandetanib if you have a certain heart problem (long QT syndrome). Before using vandetanib,certain heart problems (heart failure, slow heartbeat, QT prolongation/long QT syndrome), family history of certain heart problems (QT prolongation/long QT syndrome, sudden cardiac death). Vandetanib should not be used in people with low levels of calcium, potassium, or magnesium in the blood. Low levels of these minerals may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. To lower your risk, your doctor will check your mineral levels with a blood test and your heart with a test (EKG) before and periodically during treatment. Low mineral levels should be corrected before you start treatment. If you develop QT prolongation, your doctor may stop treatment for a while and restart it at a lower dose, and check your EKG again. Since vandetanib stays in your body for a long time, it may take a while for side effects such as QT prolongation to go away after you stop taking it. Discuss the risks and benefits of treatment with your doctor. Caprelsa is only available through a restricted program from certified prescribers and pharmacies called the Vandetanib REMS Program. These requirements apply in the United States. If you live in Canada or any other country, consult your doctor and pharmacist for your country's regulations.
How to Use Caprelsa
Read the Medication Guide provided by your pharmacist before you start taking vandetanib and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Caprelsa by mouth with or without food as directed by your doctor, usually once daily. Swallow Caprelsa whole. If you cannot swallow the tablets whole, place your dose in a glass of non-carbonated water (2 ounces or 60 milliliters) and stir for about 10 minutes until the tablet has broken apart. Note that the tablet will not completely dissolve. Do not use other liquids. Swallow the mixture right away. Rinse the glass with 4 ounces (120 milliliters) of non-carbonated water, stir to mix, and then swallow. Do not break or crush the tablets. Do not touch the dust or powder from Caprelsa. Since Caprelsa can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle Caprelsa or breathe the dust from the tablets. If contact occurs, wash the area thoroughly. The Dosage of Caprelsa is based on your medical condition and response to treatment. Take Caprelsa regularly to get the most benefit from it. To help you remember, take it at the same time each day. Tell your doctor if your condition worsens.
Before taking vandetanib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Caprelsa may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Caprelsa, tell your doctor or pharmacist your medical history,kidney disease, high blood pressure, recent bleeding (including recently coughing up blood), recent surgery/injury. Caprelsa may cause blurred vision. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely. Caprelsa may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Get medical help right away if you get sunburned or have skin blisters/redness. Follow these instructions while taking vandetanib and for 4 months after stopping treatment. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Caprelsa may cause wounds to heal slowly or poorly. Before having surgery, talk with your doctor about the risks and benefits of Caprelsa. Your doctor may tell you to temporarily stop treatment with Caprelsa at least 1 month before surgery. Ask your doctor for specific instructions about when to stop and when to restart treatment with vandetanib. Tell your doctor right away if you have wounds that are not healing well. Older adults may be more sensitive to the side effects of Caprelsa, especially QT prolongation (. Since Caprelsa can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle Caprelsa or breathe the dust from the tablets. Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using vandetanib. Vandetanib may harm an unborn baby. Ask about reliable forms of birth control while using Caprelsa and for 4 months after stopping treatment. If you become pregnant, talk to your doctor right away about the risks and benefits of Caprelsa. It is unknown if Caprelsa passes into breast milk. Because of the possible risk to the infant, breast-feeding is not recommended while using Caprelsa and for 4 months after stopping treatment. Consult your doctor before breast-feeding.
If you miss a dose of Caprelsa, take it as soon as you remember if it is more than 12 hours before the next dose. If it is less than 12 hours before the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Many drugs besides vandetanib may affect the heart rhythm (QT prolongation), including amiodarone, chloroquine, disopyramide, dofetilide, dolasetron, granisetron, haloperidol, methadone, moxifloxacin, pimozide, procainamide, sotalol, macrolide antibiotics (such as clarithromycin), among others. Other medications can affect the removal of vandetanib from your body, which may affect how vandetanib works. Examples include dexamethasone, St. John's wort, rifamycins (such as rifabutin, rifampin), drugs used to treat seizures (such as carbamazepine, phenytoin, phenobarbital, primidone), among others.
Caprelsa Side Effects
What are Caprelsa side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Caprelsa may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Caprelsa as a result of an interaction with other medications.
Side Effects of Caprelsa
The side effects of Caprelsa may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Caprelsa. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Caprelsa may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Caprelsa, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Caprelsa.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Caprelsa, or any other medication, should contact their physician. General information about Caprelsa and the side effects associated with Caprelsa are described in the following:
Common Caprelsa Side Effects
- prolonged QT interval
- increased alanine transaminase
- skin rash
- acneiform eruption
- headache disorder
- acute abdominal pain
- dry skin
- blurred vision
- upper respiratory infection
Less Frequent Caprelsa Side Effects
- cardiac arrhythmia
- cerebral ischemia
- thrombocytopenic disorder
- hypoglycemic disorder
- skin photosensitivity
- pruritus of skin
- corneal opacity
- skin inflammation
- nail disorders
- muscle spasm
Rare or Very Rare Caprelsa Side Effects
- torsades de pointes
- Stevens-Johnson syndrome
- interstitial lung disease
- palmar-plantar erythrodysesthesia
- heart failure
- posterior reversible encephalopathy syndrome
- acute respiratory insufficiency
- aspiration pneumonia
- bacterial sepsis
- intestinal perforation
- toxic epidermal necrolysis
- impaired wound healing
- arterial dissection
- arterial aneurysm
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Caprelsa when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.