Matulane

See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.diet pills/appetite suppressants (such as diethylpropion), drugs for attention deficit hyperactivity-ADHD (such as atomoxetine, methylphenidate), apraclonidine, bupropion, buspirone, carbamazepine, cyclobenzaprine, deutetrabenazine, dextromethorphan, methyldopa, metoclopramide, tetrabenazine, valbenazine, certain opioid medications (such as meperidine, methadone, tapentadol), certain supplements (such as tryptophan, tyramine), certain "triptans" used to treat migraine headaches (such as rizatriptan, sumatriptan), certain drugs for Parkinson's disease (entacapone, levodopa, tolcapone). The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/ "ecstasy," St. John's wort, certain antidepressants (including maprotiline, mirtazapine, SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine, tricyclics such as amitriptyline/doxepin), among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs. Some products can interact with procarbazine if you take them together, or even if you take them weeks before or after taking procarbazine. Tell your doctor or pharmacist if you take anything in the list of products that may interact with Matulane, or any of the products that increase serotonin, within 2 weeks before or after taking procarbazine. Also tell them if you have taken fluoxetine within 5 weeks before starting procarbazine. Ask your doctor how much time to wait between starting or stopping any of these drugs and starting procarbazine. Taking other MAO inhibitors with Matulane may cause a serious (possibly fatal) drug interaction. Do not take any other MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with Matulane. Most MAO inhibitors should also not be taken for two weeks before and after treatment with Matulane. Ask your doctor when to start or stop taking Matulane. Before using procarbazine, report the use of drugs that may increase the risk of extremely high blood pressure (hypertensive crisis) when combined with procarbazine, including herbal products (such as ephedra/ma huang), allergy and cough-and-cold products (including dextromethorphan, decongestants such as phenylephrine/pseudoephedrine), and stimulants (such as amphetamines, ephedrine, epinephrine, phenylalanine). Procarbazine should not be used with any of these medications. Talk to your doctor or pharmacist for more details. Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, marijuana (cannabis), antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), and opioid pain relievers (such as codeine, hydrocodone). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness.