Zydeligand/or alternativesChemical Ingredient: Idelalisib
What is a generic medication?
Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.
No generic is available for Zydelig 100mg.
- Manufactured by Gilead Sciences
- Product of Canada • Shipped from Canada
- Prescription Required
No generic is available for Zydelig 100mg.
Zydelig Drug Information
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Zydelig Drug Information
Zydelig is used to treat certain types of cancer (such as chronic lymphocytic leukemia-CLL, follicular B-cell non-Hodgkin's lymphoma, small lymphocytic lymphoma-SLL). Idelalisib belongs to a class of drugs known as kinase inhibitors. It works by slowing or stopping the growth of cancer cells.
Idelalisib may cause serious (possibly fatal) liver disease. Your doctor will test your liver function while you are taking Zydelig. Tell your doctor right away if you have any symptoms of liver damage, including persistent nausea/vomiting, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine. Zydelig can cause severe diarrhea and a tear in the stomach/intestines (gastrointestinal perforation). Tell your doctor right away if you develop persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool, fever, nausea/vomiting, or dizziness/fainting. Idelalisib can cause severe (possibly fatal) lung problems (pneumonitis). Tell your doctor right away if you have any symptoms of lung problems (such as worsening cough, shortness of breath, trouble breathing, wheezing). Zydelig may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Your doctor may prescribe an antibiotic to help prevent serious infection during and after treatment with Zydelig. Carefully follow your doctor's instructions. Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, cough).
How to Use Zydelig
Read the Medication Guide provided by your pharmacist before you start taking idelalisib and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Zydelig by mouth with or without food as directed by your doctor, usually twice daily. Swallow the tablets whole. Do not chew or crush the tablets. The Dosage of Zydelig is based on your medical condition and response to treatment. Do not increase your dose or use Zydelig more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Since Zydelig can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle Zydelig or breathe the dust from the tablets.
Before taking idelalisib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Zydelig may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Zydelig, tell your doctor or pharmacist your medical history,liver disease, lung problems, stomach/intestinal ulcers, current serious infection. Idelalisib can make you more likely to get infections or may worsen any current infections. Therefore, wash your hands well to prevent the spread of infection. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details. Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while taking idelalisib. Idelalisib may harm an unborn baby. Women should ask about reliable forms of birth control while taking Zydelig and for 1 month after stopping treatment. Men should ask about reliable forms of birth control while taking Zydelig and for 3 months after stopping treatment. If you or your partner becomes pregnant, talk to your doctor right away about the risks and benefits of Zydelig. Since Zydelig can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle Zydelig or breathe the dust from the tablets. It is unknown if Zydelig passes into breast milk. Because of the possible risk to the infant, breast-feeding while using Zydelig and for 1 month after stopping treatment is not recommended. Consult your doctor before breast-feeding.
If you miss a dose of Zydelig, take it as soon as you remember unless it is more than 6 hours after the time you usually take the dose. In that case, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.bendamustine, other drugs that weaken the immune system/increase the risk of infection (such as natalizumab, rituximab). Other medications can affect the removal of idelalisib from your body, which may affect how idelalisib works. Examples include rifampin, phenytoin, carbamazepine, St. John's wort, among others. Zydelig can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include domperidone, flibanserin, ivabradine, lurasidone, midazolam, triazolam, among others.
Zydelig Side Effects
What are Zydelig side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Zydelig may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Zydelig as a result of an interaction with other medications.
Side Effects of Zydelig
The side effects of Zydelig may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Zydelig. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Zydelig may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Zydelig, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Zydelig.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Zydelig, or any other medication, should contact their physician. General information about Zydelig and the side effects associated with Zydelig are described in the following:
Common Zydelig Side Effects
- abnormal hepatic function tests
- severe diarrhea
- neutropenic disorder
- skin rash
- acute abdominal pain
Less Frequent Zydelig Side Effects
- interstitial pneumonitis
- exfoliative dermatitis
- maculopapular rash
- bacterial sepsis
- hypoglycemic disorder
- thrombocytopenic disorder
- gastroesophageal reflux disease
- headache disorder
- nasal congestion
- urinary tract infection
- general weakness
- peripheral edema
- upper respiratory infection
- night sweats
- muscle spasm
- back pain
Rare or Very Rare Zydelig Side Effects
- intestinal perforation
- Pneumocystis jirovecii pneumonia
- cytomegalovirus disease
- Stevens-Johnson syndrome
- toxic epidermal necrolysis
- progressive multifocal leukoencephalopathy
- pruritus of skin
Store at room temperature in the original container away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Zydelig when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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