Lodine

Etodolac Drug Information

• Lodine Overview

  Etodolac is used to relieve pain from various conditions. It also reduces pain, swelling, and joint stiffness from arthritis. Lodine is known as a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation. If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain.

• Lodine Warnings

  Nonsteroidal anti-inflammatory drugs (including etodolac) may rarely increase the risk for a heart attack or stroke. This effect can happen at any time while taking Lodine but is more likely if you take it for a long time. The risk may be greater if you have heart disease or increased risk for heart disease (for example, due to smoking, family history of heart disease, or conditions such as high blood pressure or diabetes). Do not take Lodine right before or after heart bypass surgery (CABG). Lodine may rarely cause serious (rarely fatal) bleeding from the stomach or intestines. This effect can occur without warning at any time while taking Lodine. Older adults may be at higher risk for this effect. (See also Precautions and Drug Interactions sections.)black/tarry stools, persistent stomach/abdominal pain, vomit that looks like coffee grounds, chest/jaw/left arm pain, shortness of breath, unusual sweating, confusion, weakness on one side of the body, slurred speech, sudden vision changes. Talk to your doctor or pharmacist about the benefits and risks of taking Lodine.

• How to Use Lodine

  Read the Medication Guide provided by your pharmacist before you start using etodolac and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Lodine by mouth as directed by your doctor, usually 2 or 3 times a day with a full glass of water (8 ounces/240 milliliters). Do not lie down for at least 10 minutes after taking Lodine. To prevent stomach upset, take Lodine with food, milk, or an antacid. The Dosage of Lodine is based on your medical condition and response to treatment. To reduce your risk of stomach bleeding and other side effects, take Lodine at the lowest effective dose for the shortest possible time. Do not increase your dose or take it more often than directed. For ongoing conditions such as arthritis, continue taking Lodine as directed by your doctor. If you are taking Lodine "as needed" (not on a regular schedule), remember that pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well. For certain conditions (such as arthritis), it may take up to two weeks of taking Lodine regularly until you get the full benefit. Tell your doctor if your condition does not improve or if it worsens.

• Lodine Precautions

  Before taking etodolac, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs (such as ibuprofen, naproxen, celecoxib); or if you have any other allergies. Lodine may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before taking Lodine, tell your doctor or pharmacist your medical history,asthma (including a history of worsening breathing after taking aspirin or other NSAIDs), blood disorders (such as anemia, bleeding/clotting problems), growths in the nose (nasal polyps), heart disease (such as previous heart attack), high blood pressure, liver disease, stroke, throat/stomach/intestinal problems (such as bleeding, heartburn, ulcers). Kidney problems can sometimes occur with the use of NSAID medications, including etodolac. Problems are more likely to occur if you are dehydrated, have heart failure or kidney disease, are an older adult, or if you take certain medications (see also Drug Interactions section). Drink plenty of fluids as directed by your doctor to prevent dehydration and tell your doctor right away if you have a change in the amount of urine. Lodine may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana (cannabis). This medicine may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Limit alcohol and stop smoking. Consult your doctor or pharmacist for more information. Lodine may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults may be more sensitive to the side effects of Lodine, especially stomach/intestinal bleeding, kidney problems, and worsening heart problems. Before using Lodine, women of childbearing age should talk with their doctor(s) about the benefits and risks (such as miscarriage, trouble getting pregnant). Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, Lodine should be used only when clearly needed. It is not recommended for use during the first and last trimesters of pregnancy due to possible harm to the unborn baby and interference with normal labor/delivery. It is unknown if Lodine passes into breast milk. Consult your doctor before breast-feeding.

• Lodine Misdose

  If you are taking Lodine on a regular schedule (not just "as needed") and you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

• Lodine Interactions

  Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.aliskiren, ACE inhibitors (such as captopril, lisinopril), angiotensin II receptor blockers (such as losartan, valsartan), cidofovir, corticosteroids (such as prednisone), lithium, "water pills" (diuretics such as furosemide). Lodine may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Examples include anti-platelet drugs such as clopidogrel, "blood thinners" such as dabigatran/enoxaparin/warfarin, among others. Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs such as celecoxib, ibuprofen, or ketorolac). These drugs are similar to etodolac and may increase your risk of side effects if taken together. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually at dosages of 81-325 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details. Lodine may affect certain laboratory tests, possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Lodine.

• Lodine Side Effects

  What are Lodine side effects?

  Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Lodine may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Lodine as a result of an interaction with other medications.

  Side Effects of Lodine

  The side effects of Lodine may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Lodine. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Lodine may also occur as a result of an interaction with certain herbal supplements, foods or drinks.

  Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Lodine, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Lodine.

  By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Lodine, or any other medication, should contact their physician. General information about Lodine and the side effects associated with Lodine are described in the following:

  Common Lodine Side Effects

  Severe

  Less Severe

  • gastric acid hypersecretory conditions
  • dizziness
  • fatigue
  • headache disorder
  • nausea
  • flatulence
  • diarrhea
  • acute abdominal pain

  Less Frequent Lodine Side Effects

  Severe

  • mood changes
  • depression
  • diplopia
  • blurred vision
  • visual changes
  • tinnitus
  • esophageal ulcer
  • gastric ulcer
  • peptic ulcer
  • gastrointestinal ulcer
  • gastritis
  • bloody stools
  • gastrointestinal hemorrhage
  • pruritus of skin
  • altered mental status
  • fever
  • skin rash
  • bloody vomit
  • dysuria
  • increased urinary frequency

  Less Severe

  • constipation
  • abdominal distension
  • nervousness
  • irritability

  Rare or Very Rare Lodine Side Effects

  Severe

  • bacterial sepsis
  • body fluid retention
  • anemia
  • thrombocytopenic disorder
  • leukopenia
  • acute confusion
  • conjunctivitis
  • hypertension
  • cardiac arrhythmia
  • chronic heart failure
  • ecchymosis
  • laryngeal edema
  • pneumonia
  • asthma
  • pulmonary infiltrates
  • respiratory depression
  • bronchospastic pulmonary disease
  • aphthous stomatitis
  • esophagitis
  • colitis
  • hepatitis
  • interstitial nephritis
  • kidney stone
  • kidney disease with reduction in GFR
  • cystitis
  • hematuria
  • hyperkalemia
  • allergic dermatitis
  • bullous dermatitis
  • Stevens-Johnson syndrome
  • abnormal desquamation
  • urticaria
  • coma
  • hallucinations
  • syncope
  • tonic clonic seizure
  • edema
  • jaundice
  • polydipsia
  • exfoliative dermatitis
  • shock
  • lymphadenopathy
  • wheezing
  • dyspnea
  • chest tightness
  • proteinuria
  • crystalluria
  • abnormal hepatic function tests
  • bruising
  • anaphylaxis
  • angioedema
  • aplastic anemia
  • acute myocardial infarction
  • cerebrovascular accident
  • hypersensitivity angiitis
  • gastrointestinal perforation
  • drug-induced hepatitis
  • nephrotoxicity
  • toxic epidermal necrolysis
  • tachycardia

  Less Severe

  • symptoms of anxiety
  • nightmares
  • photophobia
  • hearing loss
  • xerostomia
  • mouth irritation
  • skin photosensitivity
  • drowsy
  • vertigo
  • insomnia
  • tremor
  • flushing
  • anorexia
  • palpitations
  • vomiting
  • polyuria
  • dysgeusia

• Lodine Storage

  Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Lodine when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.