Buy Salsalate Online

(Salsalate)

Salsalate belongs to the salicylate family of NSAIDs and works by reducing inflammation in the body. Its mechanism of action involves inhibiting enzymes that produce prostaglandins.

Prostaglandins are substances in the body that contribute to inflammation, swelling, and pain. By blocking cyclooxygenase enzymes responsible for prostaglandin production, salsalate helps reduce inflammation and discomfort.

Because of this anti-inflammatory action, salsalate is often used in conditions such as rheumatoid arthritis and osteoarthritis, where inflammation in the joints causes pain and stiffness.

Unlike some other NSAIDs, salsalate may have a slightly different effect on platelets and stomach irritation compared with certain traditional NSAIDs such as ibuprofen or naproxen.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Salsalate. However, the following is a synopsis of the general guidelines for the use of Salsalate:

• Take Salsalate exactly as prescribed by your healthcare provider.
• The medication is taken orally in tablet form.
• It may be taken with food or milk to reduce stomach upset.
• Swallow the tablets with a full glass of water.
• Take the medication at evenly spaced intervals to maintain consistent levels in the body.
• Do not exceed the prescribed dose.

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.

Some mild or common side effects of Salsalate seen in clinical trials include:

• Upset stomach.
• Stomach pain.
• Heartburn.
• Nausea.
• Headache.
• Dizziness.

Some individuals may experience serious side effects while using Salsalate. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Signs of stomach bleeding, such as vomiting blood or material that looks like coffee grounds.
• Severe allergic reaction, including hives, swelling of the face, tongue, or throat, and shortness of breath.
• Chest pain or symptoms of a heart attack.
• Stroke: chest pain, trouble breathing, weakness in one part of your body or face, slurred speech
• Heart failure: difficulty breathing, swelling, fast heartbeat
• Liver problems: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion, dark or brown urine
• Kidney problems: tiredness, dry and itchy skin, low appetite, urinating less than usual, foamy or bloody urine, muscle cramps

Disclaimer: These are not all of the possible side effects of Salsalate. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Salsalate, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• Heart disease or a history of heart attack.
• High blood pressure.
• Heart failure.
• Kidney disease.
• Liver disease.
• Stomach ulcers or gastrointestinal bleeding.

Like other nonsteroidal anti-inflammatory drugs, salsalate may increase the risk of serious cardiovascular events such as a heart attack or stroke.

• Salicylates may also increase the risk of Reye's syndrome when used in children or teenagers with viral infections such as chickenpox or influenza.
• Patients should discuss all prescription drugs, supplements, and over-the-counter medications with their healthcare provider before starting treatment.

Boxed Warning

Cardiovascular risks

• NSAIDs can increase the risk of serious heart and blood vessel events such as heart attack (MI) and stroke, which may be fatal.
• The longer they are used, the higher the risk may become.
• People who already have heart disease or cardiovascular risk factors are at greater risk.
• NSAIDs must not be used for pain after coronary artery bypass graft (CABG) surgery, because they increase the chance of heart attack and stroke.

Gastrointestinal (GI) risks

• NSAIDs can cause serious stomach and intestinal problems, including bleeding, ulcers, and perforation, which can be fatal.
• These problems can occur at any time during use, even without warning symptoms.
• Older adults are at higher risk of these serious GI complications.

Salsalate should not be used in patients with:

• Hypersensitivity or allergic reaction to salicylates.
• Severe allergic reactions to NSAIDs.
• Recent coronary artery bypass graft (CABG) surgery.

Salsalate may begin reducing pain and inflammation within several days of treatment. However, the full anti-inflammatory effects may take longer, depending on the severity of the condition.

Patients with arthritis may need to take the medication regularly to maintain symptom control.

When Salsalate is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Warfarin or other blood thinners, which may increase the risk of bleeding.
• Methotrexate, which may increase the risk of toxicity when combined with salicylates.
• Lithium, which may increase lithium levels in the body.
• Other NSAIDs, such as ibuprofen or naproxen, may increase the risk of stomach bleeding.
• Prednisone or other corticosteroids, which may increase the risk of gastrointestinal irritation.

Salsalate is available as oral tablets.

Common tablet strengths include:

500 mg tablets.

750 mg tablets.

The appropriate dosage depends on the condition being treated and the patient's response to therapy. Healthcare providers will determine the correct dose.

It should be stored at room temperature, away from the reach of children or pets.

Salsalate has been manufactured by several pharmaceutical companies and has been marketed under brand names such as Disalcid and Salsitab.

Yes, salsalate is available as a generic medication and may be sold under several brand names.

Do not stop taking Salsalate without consulting your healthcare provider. Your healthcare provider will determine whether the medication should be discontinued or adjusted.

Stopping treatment suddenly may allow inflammation and pain symptoms to return.

If you're pregnant or thinking of becoming pregnant, speak with your provider before using salsalate. You'll need to avoid taking salsalate during the second half of pregnancy (week 20 of pregnancy or later) because it might cause harm to your unborn baby or complications during delivery.

Talk to your doctor if you are breastfeeding or if you have any plans to breastfeed. Your healthcare provider will determine whether treatment with salsalate is appropriate.