Pennsaid

(Diclofenac Sodium)

Pennsaid is a topical nonsteroidal anti-inflammatory drug (NSAID) that helps in managing pain from conditions including osteoarthritis of the knee. Some common side effects of this medication include application site reactions like dryness, redness, stinging, and itching.

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Brand Versions

Pennsaid Prescription Required

Strength
1.5%
Country
Canada
Select Quantity

Currently Unavailable

Generic Versions
What are generics?

Diclofenac Sodium Prescription Required

Strength
1.5%
Country
Canada
Select Quantity

Marketed as Taro-Diclofenac in Canada

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Important information about Pennsaid

How does Pennsaid work?

The active ingredient in Pennsaid is diclofenac sodium. This painkiller works by inhibiting the COX enzymes, which in turn reduces the formation of prostaglandins. These prostaglandins are markers of inflammation and can cause symptoms of fever and pain. By decreasing the synthesis of prostaglandins, the symptoms of pain will be reduced.

How do you use Pennsaid?

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Pennsaid. However, the following is a synopsis of the general guidelines for the use of Pennsaid:

  • The topical solution should be applied to clean, dry skin, and the application site should be free of open wounds. When ready, apply the medication to the affected area and wash your hands after application. Before applying sunscreen or lotion, ensure the area is dry.
  • If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.

What are the side effects of Pennsaid?

The most common side effects of Pennsaid seen in clinical trials include:

  • Redness, dryness, stinging, itching, and rash at the application site
  • Drowsiness
  • Heartburn and gas
  • Gastrointestinal/abdominal pain
  • Diarrhea
  • Nausea

Some individuals may experience serious side effects while using Pennsaid. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Heart failure and high blood pressure: shortness of breath, swelling of the ankles, feet, or hands, blurred vision, sudden weight gain, unusual weakness or fatigue
  • Stomach bleeding or perforation: vomiting blood, dark or bloody stools, and severe stomach pain
  • Severe kidney problems: fatigue, dry and itchy skin, loss of appetite, urinating less than usual, bloody urine, and muscle cramps
  • Stroke: chest pain, shortness of breath, weakness on one side of your body or face, and slurred speech
  • Severe liver problems: abdominal swelling, yellowing of your skin or eyes (jaundice), and dark urine
  • Severe allergic or skin reactions: skin rash, dermatitis, reddening, peeling, or blisters, trouble breathing

These are not all of the possible adverse events of Pennsaid. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

What are the warnings or precautions for Pennsaid?

Before starting Pennsaid, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether you have:

  • High blood pressure (hypertension), heart disease, or a previous heart attack or stroke
  • Fluid retention or edema
  • Stomach ulcer
  • Kidney problems
  • Liver cirrhosis
  • Asthma
  • Bleeding problems

Boxed Warning

  • There is an increased risk of bleeding in the stomach and an increased risk of a heart attack and stroke, which could be fatal.

Are there any contraindications with Pennsaid?

  • If an allergic reaction occurs to Pennsaid, this can include signs such as hives and difficulty breathing.
  • Right before or after a type of open heart surgery called coronary artery bypass graft surgery (CABG).

How long does it take Pennsaid to work?

The medication will begin working within a few minutes to an hour.

What interacts with Pennsaid?

When Pennsaid is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

  • Other topical or oral nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, aspirin, and naproxen
  • Blood thinners, including warfarin
  • Diuretics
  • Lithium
  • Methotrexate
  • Cyclosporine
  • Corticosteroids

What doses of Pennsaid are available?

The dosage form and strength for Pennsaid is a 1.5% diclofenac sodium topical solution.

How do I store Pennsaid?

Pennsaid topical solution should be stored at room temperature and away from the reach of children.

Which pharmaceutical company manufactures Pennsaid?

The pharmaceutical company that manufactures Pennsaid is Nuvo Pharmaceuticals Inc.

Is there a generic version of Pennsaid?

There are lower-cost alternatives for the brand-name Pennsaid and Voltaren.

How do I stop taking Pennsaid?

Pennsaid can be stopped without tapering according to the product information.

Can Pennsaid be used if I am pregnant?

This medication can cause toxicity to the unborn baby, especially during the third trimester. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Can Pennsaid be used if I am breast feeding?

It is unknown if Pennsaid can pass into the breastmilk, but it is best to avoid it while breastfeeding to avoid causing significant harm to the baby. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.

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Important information about buying Pennsaid from UniversalDrugstore™

What happens after I place my order for Pennsaid with Universal Drugstore?

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

How long does it take to process and deliver my order for Pennsaid?

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Can I track my order of Pennsaid?

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

What should I do if there is an issue with my order for Pennsaid?

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

How is my medication packaged to ensure privacy and safety?

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Does Universal Drugstore ship medications that require refrigeration or special handling?

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

What are the shipping costs, and does Universal Drugstore offer free delivery?

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Does Universal Drugstore accept Medicare or Medicaid for prescriptions?

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Can I use private health insurance to cover my prescription from Universal Drugstore?

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Unievrsal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

How secure is my payment information when ordering from Universal Drugstore?

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Can I order a generic alternative to Pennsaid?

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

Do I need a prescription to order Pennsaid?

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.

Can I order multiple medications at once?

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Can I refill my prescription through Universal Drugstore?

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Does Universal Drugstore offer discounts or price matching?

Yes! We offer:

  • Up to 80% savings on medications
  • Price match guarantee – we’ll match competitor pricing on qualifying medications
  • 10% off your first order for new customers

How can I contact Universal Drugstore for additional support?

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

Important

The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.