Cortifoam

(Hydrocortisone Acetate)

The active ingredient in Cortifoam is hydrocortisone. Hydrocortisone is a corticosteroid that helps reduce inflammation in the rectal area.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Cortifoam. However, the following is a synopsis of the general guidelines for the use of Cortifoam:

• Cortifoam is for rectal use only.
• The foam is inserted using the applicator included with the product.
• Shake the aerosol container well before use.
• The usual schedule is once or twice daily, depending on your healthcare provider’s instructions.
• Try to empty your bowel first so the medicine stays in place longer.
• After inserting the foam, remain lying on your side for a short period to help the medicine spread.
• If you miss a dose, use it when you remember. If it is close to the next dose, skip the missed dose. Do not double up.
• Use Cortifoam exactly as long as your healthcare provider recommends. Stopping too suddenly may cause symptoms to return.

Some mild or common side effects of Cortifoam include:

• Rectal pain or discomfort.
• Dryness or irritation at the application site.
• Bruising.

Some individuals may experience serious side effects while using Cortifoam. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Signs of infection, such as fever, chills, or worsening rectal bleeding.
• Severe allergic reactions, including hives, swelling, or difficulty breathing.
• Vision changes that may suggest cataracts or glaucoma.
• Muscle weakness or myopathy.
• Personality changes, confusion, or psychosis.
• Slowed wound healing.
• Symptoms of adrenal gland suppression, such as extreme tiredness or weakness.
• High blood pressure or increased fluid retention.
• Very low potassium, which may appear as irregular heartbeat or muscle cramps.
• Abscess or perforation in the rectal area.

These are not all of the possible side effects of Cortifoam. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Cortifoam, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• Fungal infections, as corticosteroids can worsen them.
• A history of tuberculous infections.
• Recent exposure to chickenpox or measles.
• Glaucoma or cataracts.
• Thyroid problems that may affect steroid metabolism.
• Stomach or intestinal issues such as a peptic ulcer or fistulas.
• Rectal abscess or obstruction.
• Myasthenia gravis or other conditions that weaken muscles.
• Heart failure, high blood pressure, or a history of heart attack.
• Mood disorders or previous steroid-related personality changes.
• Diabetes, as steroids may raise blood glucose.
• Osteoporosis risk.
• Difficulty fighting infections or signs of weakened immunity.
• Any recent vaccinations, including live vaccines, which may interact with corticosteroid use.

Cortifoam should not be used in individuals who have:

• Known hypersensitivity to hydrocortisone or any component of the product.
• Systemic fungal infections.
• Intestinal perforation or widespread abscess in the rectal area.

Many people begin to notice improvement in symptoms within a few days, though full benefit may take one to two weeks. Your healthcare provider may adjust the length of treatment depending on how you respond.

When Cortifoam is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Warfarin, because corticosteroids may change blood-thinning effects.
• NSAIDs, because the combination may raise the risk of stomach irritation or peptic ulcer.
• Amphotericin B or diuretics, because they may increase the chance of low potassium.
• Thyroid medications, because thyroid function affects steroid levels.
• Supplements that alter potassium balance.
• Other corticosteroids, which may add to systemic steroid exposure.

Cortifoam is available as a rectal foam containing 10 percent hydrocortisone. Each aerosol container includes a measured delivery system and applicator.

Store at room temperature and keep out of reach of children.

Cortifoam is manufactured by Allergan.

Yes. Hydrocortisone rectal foam is the generic name and may be available depending on market supply.

Do not stop Cortifoam suddenly unless your healthcare provider instructs you to do so. They may advise gradually reducing how often you use it to help your adrenal glands adjust. If symptoms return after stopping, contact your healthcare provider for medical advice.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.