Entocort Enema

The active ingredient in Entocort Enema is budesonide. This medication falls under the medication class named glucocorticosteroid. It mimics the action of cortisol, which is a hormone that regulates the immune response and inflammation. Overall, it is an anti-inflammatory medication.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Entocort Enema. However, the following is a synopsis of the general guidelines for the use of Entocort Enema:

• This medication should be administered at bedtime.
• Follow these instructions when using the budesonide enema:
• Remove the protective cap and nozzle from the bottle.
• Insert the dispersible tablet from the aluminum foil pack and place it inside the bottle.
• Place the cap and nozzle back on. Shake the bottle for 10 seconds or until the tablet has dissolved. The solution should be a pale yellow color.
• Put your hand through the plastic bag to protect your hand. After this, grab the bottle.
• While lying down on your left side, shake the bottle and then remove the protective cap. Insert the nozzle into the rectum and empty the contents.
• Remove the applicator and pull the plastic bag over it.
• Roll onto your stomach and stay in that position for 5 minutes.
• In the case of missed doses, it is not necessary to make it up. Ensure you continue with the next dose as prescribed.

The most common side effects of Entocort Enema include:

• Diarrhea
• Nausea
• Skin rash or irritation
• Gas

Some individuals may experience serious side effects while using Entocort Enema. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe allergic reaction: swelling of the tissues and difficulty breathing
• Weakened bones and osteoporosis
• Adrenal insufficiency
• Changes in your mood or behavior
• Visual disturbances or blurred vision
• Muscle twitching

These are not all of the possible side effects of Entocort Enema. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Entocort Enema, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether you have:

• Family history of high blood pressure
• Liver disease
• Kidney problems
• Stomach or peptic ulcers
• Heart disease
• Past infections, including hepatitis B
• Bone problems such as osteoporosis
• Myasthenia gravis
• Diabetes
• Previous vaccines for measles or chickenpox
• History of cataracts or glaucoma
• History of herpes infection
• Adrenal gland problems

• Known allergy to Entocort Enema or any of its inactive ingredients, including sodium chloride, magnesium stearate, lactose anhydrous, polyvidone, and riboflavin.
• Known allergy to medications in the same drug class

The full effect of budesonide will take about 2 to 4 weeks.

When Entocort Enema is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Medication used for fungal infections, including fluconazole, itraconazole, and ketoconazole
• Medications used for HIV, including ritonavir
• Proton pump inhibitors
• Antacid
• Medications that contain a corticosteroid
• Medications that suppress the immune system, including cyclosporine
• Erythromycin
• H2 antagonists, including famotidine
• Grapefruit juice
• Cobicistat-containing products

This product is available as a 0.02 mg/mL budesonide enema.

Entocort Enema should be stored at room temperature and out of the reach of children.

The pharmaceutical company that manufactures Entocort Enema is Tillotts Pharma.

There are lower-cost alternatives for the brand names Entocort EC, Uceris, and Tarpeyo.

Entocort Enema does require tapering, and the tapering schedule should be discussed with the doctor.

Entocort Enema may be a safe option to use if you are pregnant. However, you should talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Budesonide can pass through the breastmilk and could affect the baby. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.