Advair HFA

Advair HFA Drug Information

• Advair HFA Overview

  Advair HFA is used to control and prevent symptoms (wheezing and shortness of breath) caused by asthma.fluticasone and salmeterol. Fluticasone belongs to a class of drugs known as corticosteroids. It works by reducing the irritation and swelling of the airways. Salmeterol belongs to the class of drugs known as long-acting beta agonists. It works by opening airways in the lungs to make breathing easier. Controlling symptoms of breathing problems can decrease time lost from work or school. When used alone, long-acting beta agonists (such as salmeterol) may rarely increase the risk of serious (sometimes fatal) asthma-related breathing problems. However, combination inhaled corticosteroid and long-acting beta agonists, such as Advair HFA, do not increase the risk of serious asthma-related breathing problems. Advair HFA should be used when breathing problems are not well controlled with one asthma-control medication (such as inhaled corticosteroid) or if your asthma symptoms need combination treatment. Before using Advair HFA, it is important to learn how to use it properly. Advair HFA must be used regularly to be effective. It does not work right away and should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler (such as albuterol, also called salbutamol in some countries) as prescribed.

• How to Use Advair HFA

  Read the Patient Information Leaflet and Instructions for Use provided by your pharmacist before you start using Advair HFA and each time you get a refill. Follow the illustrated directions for the proper use of Advair HFA. If you have any questions, ask your doctor or pharmacist. Follow the instructions for priming the inhaler if you are using it for the first time, if you have not used it for a long time (depending on your product, for more than 1 week or 4 weeks), or if you dropped the inhaler. When priming the inhaler, make sure to spray away from the face so that you do not get the medication into your eyes. Shake the inhaler well for 5 seconds before each use. Inhale Advair HFA by mouth as directed by your doctor, usually twice daily (in the morning and evening, 12 hours apart). If two inhalations/puffs are prescribed, wait about 30 seconds between them. Shake the inhaler well between each puff. If you are using other inhalers at the same time, wait at least 1 minute between using each medication, and use Advair HFA last. Gargle and rinse your mouth with water after each use of Advair HFA to help prevent irritation and yeast infections (thrush) in the mouth and throat. Do not swallow the rinse water. Clean the inhaler at least once a week as directed. The Dosage of Advair HFA is based on your medical condition and response to treatment. Use Advair HFA regularly in order to get the most benefit from it. Advair HFA works best if used at evenly spaced times. To help you remember, use it at the same times each day. Do not increase your dose, use Advair HFA more often, or stop using it without first consulting your doctor. Also, do not use other long-acting beta agonists while using Advair HFA. If you have been using a quick-relief inhaler (such as albuterol, also called salbutamol in some countries) on a regular daily schedule (such as 4 times daily), you must stop this schedule and only use the quick-relief inhaler as needed for sudden shortness of breath/asthma attacks. Consult your doctor for details. If you are regularly taking a different corticosteroid by mouth (such as prednisone), you should not stop taking it unless directed by your doctor. Some conditions (such as asthma, allergies) may become worse when the drug is suddenly stopped. If you suddenly stop taking the drug, you may also have withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness). To help prevent withdrawal, your doctor may slowly lower the dose of your old medication after you begin using fluticasone/salmeterol. Tell your doctor or pharmacist right away if you have withdrawal. See also Precautions section. It may take 1 week or longer before you get the full benefit of Advair HFA. Tell your doctor if your symptoms do not improve or if they worsen. Learn which of your inhalers you should use every day (controller drugs) and which you should use if your breathing suddenly worsens (quick-relief drugs). Ask your doctor ahead of time what you should do if you have new or worsening cough or shortness of breath, wheezing, increased sputum, worsening peak flow meter readings, waking up at night with trouble breathing, if you use your quick-relief inhaler more often (more than 2 days a week), or if your quick-relief inhaler does not seem to be working well. Learn when you can treat sudden breathing problems by yourself and when you must get medical help right away.

• Advair HFA Precautions

  Before using Advair HFA, tell your doctor or pharmacist if you are allergic to fluticasone or salmeterol; or if you have any other allergies. Advair HFA may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Advair HFA, tell your doctor or pharmacist your medical history,current/past infections (such as tuberculosis, herpes), high blood pressure, bone loss (osteoporosis), heart disease (such as chest pain, heart attack, irregular heartbeat), overactive thyroid (hyperthyroidism), diabetes, eye problems (such as cataracts, glaucoma), seizures, liver disease. Salmeterol may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using Advair HFA,certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death). Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using Advair HFA safely. Advair HFA may mask signs of infection. It can make you more likely to get infections or may worsen any current infections. Therefore, wash your hands well to prevent the spread of infection. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details. If you have switched from a corticosteroid taken by mouth (such as prednisone tablets) to this inhaler within the past 12 months, or if you have been using Advair HFA in higher-than-usual doses for a long time, it may be more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using Advair HFA or have used a corticosteroid taken by mouth within the past 12 months. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. Carry a warning card or medical ID bracelet that says you use (or have used) corticosteroid medications. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults with COPD may be at greater risk for pneumonia while using Advair HFA. Older adults may also be more sensitive to the side effects of Advair HFA, especially QT prolongation (see above). Advair HFA may temporarily slow down a child's growth if used for a long time. However, poorly controlled asthma can also slow down growth. See the doctor regularly so your child's height can be checked. During pregnancy, Advair HFA should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if Advair HFA passes into breast milk. Consult your doctor before breast-feeding.

• Advair HFA Misdose

  If you miss a dose of Advair HFA, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

• Advair HFA Interactions

  Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.aldesleukin. Other medications can affect the removal of fluticasone and salmeterol from your body, which may affect how Advair HFA works. Examples include azole antifungals (such as ketoconazole), boceprevir, cobicistat, macrolide antibiotics (such as clarithromycin), HIV protease inhibitors (such as lopinavir, ritonavir), nefazodone, telithromycin, among others.

• Advair HFA Side Effects

  What are Advair HFA side effects?

  Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Advair HFA may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Advair HFA as a result of an interaction with other medications.

  Side Effects of Advair HFA

  The side effects of Advair HFA may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Advair HFA. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Advair HFA may also occur as a result of an interaction with certain herbal supplements, foods or drinks.

  Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Advair HFA, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Advair HFA.

  By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Advair HFA, or any other medication, should contact their physician. General information about Advair HFA and the side effects associated with Advair HFA are described in the following:

  Common Advair HFA Side Effects

  Severe

  • bronchitis

  Less Severe

  • headache disorder
  • oral candidiasis
  • pharyngeal candidiasis
  • pharyngitis
  • upper respiratory infection
  • sinusitis
  • myalgias
  • headache disorder
  • cough

  Less Frequent Advair HFA Side Effects

  Severe

  Less Severe

  • sore throat
  • rhinitis
  • nasal congestion
  • influenza
  • cramps
  • dizziness
  • tremor
  • tachycardia
  • palpitations
  • cough
  • nausea
  • nervousness
  • voice change

  Rare or Very Rare Advair HFA Side Effects

  Severe

  • keratitis
  • conjunctivitis
  • hypertension
  • cardiac arrhythmia
  • upper respiratory infection
  • sinusitis
  • bronchitis
  • asthma exacerbation
  • laryngismus
  • paradoxical bronchospasm
  • chest pain
  • angioedema
  • hypersensitivity drug reaction
  • edema
  • stridor
  • anaphylaxis
  • hyperglycemia
  • seizure disorder
  • angina
  • hypotension
  • prolonged QT interval
  • atrial fibrillation
  • extrasystoles
  • ventricular tachycardia
  • hypercortisolism
  • aggressive behavior
  • glaucoma
  • cataracts
  • paradoxical bronchospasm
  • urinary tract infection
  • skin and skin structure infection
  • urticaria
  • osteoporosis
  • osteopenia
  • skin rash
  • hyperglycemia
  • angioedema
  • pneumonia
  • immunosuppression
  • anaphylaxis
  • hypersensitivity angiitis
  • esophageal candidiasis
  • central serous chorioretinopathy

  Less Severe

  • oral candidiasis
  • symptoms of anxiety
  • earache
  • laryngitis
  • toothache
  • eczema
  • urticaria
  • arthralgias
  • myalgias
  • insomnia
  • fever
  • skin rash
  • contact dermatitis
  • dyspepsia
  • vomiting
  • paresthesia
  • fatigue
  • malaise
  • symptoms of anxiety
  • agitation
  • hyperkinesis
  • ecchymosis
  • laryngitis
  • rhinitis
  • depression
  • dental discoloration
  • sore throat
  • xerostomia
  • pruritus of skin
  • arthralgias
  • dizziness
  • viral infection
  • fever
  • fatigue
  • weight gain
  • dyspnea
  • nausea
  • vomiting
  • diarrhea
  • irritability
  • eosinophilia
  • rhinorrhea
  • dyspepsia
  • muscle rigidity
  • dental caries
  • facial edema
  • blurred vision

• Advair HFA Storage

  Store at room temperature away from light, heat, and moisture. Do not store in the bathroom. Store the inhaler with the mouthpiece down. Do not puncture the canister or use near an open flame. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Advair HFA when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.