Kenalog Cream

(Triamcinolone Acetonide)

The active ingredient in Kenalog cream is triamcinolone acetonide, a topical corticosteroid. It works by reducing the body’s natural immune response in the affected area, which helps relieve redness, itching, and swelling caused by conditions like dermatitis, eczema, and psoriasis.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Kenalog Cream. However, the following is a synopsis of the general guidelines for the use of Kenalog Cream:

• Wash your hands before and after applying the cream unless you are treating your hands.
• Apply a thin layer of Kenalog to the affected area once or more daily, as directed by your doctor. Rub it in gently.
• Do not use more cream or use it for longer than your doctor tells you.
• Avoid covering treated skin with tight bandages, plastic pants, or occlusive dressings unless your doctor specifically tells you to, especially in the diaper area of children.
• Do not apply near the eyes, mouth, or on open wounds unless instructed.
• For missed doses, apply it as soon as you remember. If it is close to your next dose, skip the missed one and resume your regular schedule. Do not double up.

Some mild or common side effects of Kenalog Cream seen in clinical trials as compared to placebo include:

• Burning, itching, irritation, or dryness
• Redness, peeling, or a slight rash
• Acne‑like changes or small bumps
• Change in skin color or temporary hair growth in the treated area
• Blistering or thinning of the skin with long‑term use

Some individuals may experience serious side effects while using Kenalog Cream. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Signs of a severe allergic reaction (trouble breathing, swelling of face/lips/throat, hives)
• Severe rash, infection, or worsening skin condition
• Unusual tiredness or symptoms of adrenal gland problems
• Visible signs of Cushing’s syndrome (weight gain, puffiness in the face, mood changes)

These are not all of the possible side effects of Kenalog Cream. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Kenalog Cream, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• A skin infection or signs of infection
• Diabetes or Cushing’s syndrome
• Thin skin or symptoms of skin thinning
• A history of allergic reactions to steroids or other ingredients

Kenalog cream should not be used for conditions not directed by your doctor. Avoid using it on large areas of skin, underarms, or groin, or broken skin unless your doctor tells you it’s safe. Children may absorb more of the medicine and are at higher risk of side effects.

Boxed Warning

Topical corticosteroids like Kenalog can be absorbed through the skin into the bloodstream. With long‑term use, especially over large areas or under occlusive dressings, this could affect the body’s natural hormone system (HPA axis) and cause serious side effects like adrenal suppression or Cushing’s syndrome. Your doctor will weigh risks and benefits for your situation.

• Known allergy to triamcinolone, other corticosteroids, or any ingredient in the cream
• Skin infection at the site of application (unless your doctor specifically recommends treatment for infection first)
• Open wounds or ulcerated skin, unless directed by your healthcare provider
• History of allergic reaction to other topical steroids

Tell your doctor about all other medications, OTC drugs, vitamins, and supplements you take to avoid unwanted interactions.

Some people notice relief from itching and inflammation within a few days of starting treatment. If you do not see improvement within 1–2 weeks or if your condition worsens, contact your healthcare provider.

When Kenalog Cream is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Other corticosteroid products (topical, oral, or injectable)
• Medications that affect the immune system
• Acne creams or dental paste/orabase
• Herbal supplements that affect hormone levels

Kenalog cream comes in various strengths, most commonly 0.025%, 0.1%, and 0.5% triamcinolone acetonide. Your doctor will choose the appropriate strength based on your condition.

Store Kenalog at room temperature away from heat and moisture. Do not freeze it, and keep it securely out of the reach of children.

The brand product Kenalog cream is produced by pharmaceutical companies licensed to make the brand‑name formulation. Specific manufacturers can vary by region.

Yes. The active ingredient triamcinolone topical may be available as generic products that work the same as the brand-name product, often at a lower cost.

Do not stop using Kenalog cream suddenly if you have been using it for a long time without speaking to your doctor. Your provider will guide how to taper off if needed to avoid a hormone imbalance. For short‑term treatment, you can usually stop once the course is complete and symptoms have improved.

Kenalog cream can be used during pregnancy only if your doctor determines that the benefits outweigh the potential risks. Topical corticosteroids like triamcinolone are generally considered low risk when applied to small areas of the skin, but prolonged use or application over large areas may increase risk to the adrenal gland or fetal development. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Kenalog cream may be used while breastfeeding if applied to a small area and not on the breast itself. Minimal amounts may pass into breast milk, but systemic absorption is usually low. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.