Durezol

The active ingredient in Durezol is difluprednate, which is a corticosteroid. It helps relieve eye pain, redness, and swelling by reducing ocular inflammation when given directly to the eye.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Durezol. However, the following is a synopsis of the general guidelines for the use of Durezol:

• Before using the eye drops, wash your hands.
• Pull down your lower eyelid and tilt your head back a little. With the tip down, hold the dropper above the eye.
• Keep your head tipped down and close your eyes for one to two minutes without squinting or blinking. To prevent the fluid from leaking into your tear duct, gently press your finger to the inside corner of your eye for approximately one minute.
• Don't use more drops than your doctor has prescribed. Wait roughly five minutes between drops if you use more than one.
• Before applying any additional eye drops that your doctor has ordered, wait at least ten minutes.
• Avoid putting the eye dropper directly on your eye or touching its tip. Your eye could become infected by a contaminated dropper, which could cause major visual issues.
• Wearing soft contact lenses while taking this medication is not advised. Soft contact lenses may become discoloured by a preservative used in Durezol ophthalmic emulsion. After taking this medication, wait at least ten minutes before putting in your contact lenses.
• If, after two days of treatment, your symptoms do not improve, give your doctor a call.
• You might require regular vision tests to monitor the pressure inside your eyes if you use Durezol for more than ten days.

The most common side effects of Durezol seen in clinical trials include:

• Eye swelling.
• Blurred vision.
• Eye inflammation.
• Eye irritation.
• Dry eyes.
• Sensitivity to light.
• Crusting on the eyelids.
• Vision changes.

Some individuals may experience serious side effects while using Durezol. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Hives, breathing difficulties, and facial, tongue, or throat swelling are signs of a severe allergic reaction.
• Increased intraocular pressure (IOP). Long-term use of corticosteroids like Durezol may result in increased eye pressure and glaucoma. If this medication is used for 10 days or longer, IOP should be monitored.

These are not all of the possible side effects of Durezol. You should always seek medical advice from a healthcare professional for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Durezol, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether you have:

• Glaucoma.
• Cataracts or recently had cataract surgery, as this may cause delayed healing.
• A bacterial, fungal, or viral infection of the eye (including herpes simplex), or if you are allergic to difluprednate, you should not use Durezol.

Bacterial, viral, eye infection, or fungal infection in the eye.

Durezol typically begins to work within a few days of starting treatment. Most patients notice improvement in eye inflammation and pain within 1 to 3 days, but the full effect may take up to a week, depending on the condition being treated and individual response.

When Durezol is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. There are no specific drug interactions listed for Durezol. However, it is important to let your healthcare provider know what other medications you are taking.

Durezol is available in the following dosage form and strength: 0.05% difluprednate ophthalmic emulsion. The typical dose is as follows:

Pain and inflammation in the eyes after eye surgery: One drop is usually applied to the afflicted eye four times a day during the first 24 hours following ocular surgery and for the next two weeks. After that, the dosage is usually reduced to one drop twice daily for a week. Depending on how your eye heals, your prescriber will provide you with further advice.

When treating endogenous anterior uveitis, a drop is usually applied to the afflicted eye four times a day for two weeks. Depending on your symptoms, your doctor may then gradually reduce your dosage.

If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only use the next dose.

Store at room temperature and keep out of reach of children.

Novartis is the pharmaceutical manufacturer of Durezol.

There are several generic versions available of Durezol.

If you have been taking Durezol for more than a few days, you should consult your doctor before abruptly stopping the medication. Because Durezol is a strong steroid, discontinuing medication suddenly may result in a rebound effect, which makes inflammation worse or return.

Durezol should be used during pregnancy only if the potential benefit outweighs the possible risks to the fetus. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.