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Buy Taclonex Online
(Betamethasone Dipropionate/Calcipotriol)

What is Taclonex?

What is Taclonex?

Taclonex is a prescription topical treatment used for plaque psoriasis. It combines two active ingredients, calcipotriene and betamethasone dipropionate, to help reduce inflammation, slow skin cell growth, and improve the appearance of affected areas. It is available in different dosage forms, including Taclonex ointment and topical suspension, and is applied directly to the skin at the treatment site.

Taclonex is FDA-approved and commonly prescribed by healthcare providers for adults and certain pediatric patients. It is designed for short-term use and should be applied only to the skin areas affected by psoriasis.

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Purchase Taclonex from Universal Drugstore today and save!

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  • 0.064%/0.005%

Taclonex brand

Taclonex 
0.064%/0.005%

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Prescription Required
Product of Canada

Product of Canada

Marketed as Dovobet Gel 0.05%/0.005% in Canada.

Betamethasone Dipropionate/Calcipotriol (generic Taclonex)

What are generics?

Betamethasone Dipropionate/Calcipotriol 
0.064%/0.005%

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Prescription Required
Product of Canada

Product of Canada

Marketed as Taro-Calcipotriol/Betamethasone Gel 0.05%/0.005% in Canada.

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Important information about Taclonex

The active ingredients in Taclonex are calcipotriene hydrate and betamethasone dipropionate.

Calcipotriene is a form of vitamin D that helps regulate calcium metabolism and slows down the rapid growth of skin cells seen in plaque psoriasis. Betamethasone dipropionate is a potent corticosteroid that reduces inflammation, redness, and itching by suppressing the immune response in the skin. Together, these ingredients work to improve scaling, thickness, and irritation while targeting the underlying mechanism of action involved in psoriasis.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Taclonex. However, the following is a synopsis of the general guidelines for the use of Taclonex:

  • Apply Taclonex to the affected areas of the skin once daily or as directed by your healthcare provider.
  • Wash hands before and after use, unless treating the hands.
  • Use only on plaque psoriasis areas and avoid healthy surrounding skin when possible.
  • Do not apply to the face, groin, axillae, or intravaginal areas unless- instructed.
  • Avoid covering treated skin with occlusive dressings unless directed by a healthcare professional.
  • Limit use to the recommended body surface area to reduce the risk of systemic effects.
  • Avoid excessive exposure to sunlight, sun lamps, or phototherapy during treatment.
  • Do not use on sunburned or infected skin.

Some mild or common side effects of Taclonex seen in clinical trials as compared to placebo include:

  • Skin irritation at the treatment site.
  • Burning sensations or itching (pruritus).
  • Dryness or redness of the skin.
  • Folliculitis.

Some individuals may experience serious side effects while using Taclonex. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Signs of allergic reaction, such as hives, swelling, or trouble breathing.
  • Severe skin reactions, including blistering or allergic contact dermatitis.
  • Hypercalcemia or hypercalciuria due to effects on calcium metabolism.
  • Adrenal gland suppression or HPA axis effects from topical steroid use.
  • Symptoms of Cushing's syndrome such as weight gain or thinning skin.
  • Vision problems such as glaucoma or cataracts.

These are not all of the possible side effects of Taclonex. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Taclonex, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

  • Disorders of calcium metabolism or a history of hypercalcemia.
  • Skin infections or open wounds in the treatment area.
  • Liver or kidney conditions affecting calcium balance.
  • Diabetes or risk of hyperglycemia.
  • Eye conditions such as glaucoma or cataracts.

Additional precautions:

  • Prolonged use of topical corticosteroids may lead to thinning skin or systemic absorption.
  • Avoid using large amounts or covering treated skin to reduce HPA axis suppression risk.
  • Monitor for signs of adverse reactions, especially in pediatric patients.
  • Use only as directed to avoid unwanted systemic effects.

Taclonex should not be used in the following situations:

Known hypersensitivity to calcipotriene, betamethasone dipropionate, or any inactive ingredients.

Disorders of calcium metabolism, such as hypercalcemia.

Taclonex may begin to improve plaque psoriasis symptoms within a few days to weeks. Full benefits are often seen after several weeks of consistent use, depending on the severity of the condition and response to treatment.

When Taclonex is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

  • Other topical corticosteroids, which may increase the risk of systemic corticosteroid effects.
  • Vitamin D products or supplements, which may increase the risk of hypercalcemia.
  • Phototherapy, which may increase skin sensitivity and irritation when combined.

Taclonex is available in the following dosage forms:

  • Topical ointment.
  • Topical suspension.

The amount used depends on the size of the affected skin area and should follow your healthcare provider’s instructions.

It should be stored at room temperature, away from the reach of children or pets.

Taclonex is manufactured by LEO Pharma Inc.

Yes, generic versions containing calcipotriene and betamethasone dipropionate are available.

Do not stop using Taclonex without speaking to your healthcare provider.

Sudden discontinuation may cause symptoms of plaque psoriasis to return.

Your healthcare provider may recommend tapering or switching treatments if needed.

Taclonex should only be used during pregnancy if clearly needed.

Topical corticosteroids and vitamin D analogs may be absorbed through the skin.

Controlled studies in pregnant women show no evidence of fetal risk.

Always consult your healthcare provider for medical advice before use during pregnancy.

Caution is advised when using Taclonex while breastfeeding.

It is not known if the medication passes into breast milk in significant amounts.

Avoid applying to areas that may come into contact with the infant.

Speak with your healthcare provider to determine the safest option during breastfeeding.

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Important information about buying Taclonex from UniversalDrugstore™

We ship to destinations within the United States, including Alaska and Hawaii, as well as internationally. Delivery typically takes about 2 weeks for orders shipped within the U.S. and Canada, and about 4 weeks for international orders, depending on your location and customs processing.

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Universal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

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Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Yes! We offer:

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The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.